How to Clean a Micropipette Tip

Posted by anna on April 20, 2022 

When using a micropipette, the tip is an essential part of the instrument. Without the tip, the liquid will flow in the wrong direction. In order to prevent this, a tip made from a silicone or a different polypropylene blend is used. This type of tip can prevent spreading of liquids with low surface tension, although a silicone coating can wash away with the samples. To remove the tip, pull it from the liquids by grasping the base and pulling it out. Once removed, place it in an autoclavable garbage bag or tip disposal box. Otherwise, it could become a biohazard.

The first consideration when purchasing a pipette is accuracy and precision. Choosing the wrong tip can lead to contamination, waste of samples and reagents, and repetitive stress injury. To avoid all these risks, make sure you choose a tip made from a reputable manufacturer. However, not all tips are created equal. If you are unsure of the tip's accuracy, gravimetrically test the micropipette before purchasing.

When a tip micropipette has been contaminated with a known substance, it is important to perform specific cleaning procedures. The following cleaning procedures should be followed if the tip has come into contact with aqueous solutions, organic solvents, and proteins. Rinsing the tips with ethanol is not enough if the tip is cross-contaminated with infectious liquids. For this reason, it is essential to perform autoclave testing every three to six months. Then, the pipettes should be allowed to return to room temperature.

The Eppendorf micropipette was an instant hit in Europe, but it took several years before it became common equipment in the United States. During this period, Eppendorf concentrated on technical perfection and marketing. After several years, the US market was opened up for the product, and Gilson Inc. realized the market potential. They developed their own brand of micropipette with a variable volume setting. This was an imitation of Schnitger's invention and exploited weaknesses in patent law. These micropipettes quickly became the preferred tools of many researchers.

tip micropipette

Ensure the tip of the micropipette is inserted into the sample. If not, the sample may remain in the tip. When using a disposable tip, however, it is necessary to remove the tip before performing the aspiration. The plunger helps prevent liquid from entering the shaft, and the volume markings on the tip allow you to determine the exact volume without the aid of a tape measure. When using a disposable tip, a sample with a soft stop will remain in the micropipette, while a hard stop will force air out of the sample. Whenever you need to fill up a rack of pipette tips, you should consider using an automatic pipette tip refill system. Using an automatic pipette tip refill system of Tip Loader will save you up to 75% on shipping costs. These are just some of the benefits of the automated pipette tip refill system.

The design of the tip micropipette is outlined in a patent application. The first page of the patent application shows the top part of the device. A spring-loaded piston runs in a slit at the end of the first concentric mobile cylinder. A stronger spring pushes the piston downward. The outer diameter of the tip is typically between 50 and 500 nm. There are several different types of tip micropipettes.

Benefits of Sapphire Pipette Tips

There are several benefits to using Sapphire pipette tips in your laboratory experiments. This pipette comes in eight different sizes, from 10 ul to 1250 ul. They are available in refill units, bags, and racks. There is also an extended tip for smaller volumes. To help you find the perfect tip for your experiment, here are a few helpful tips. If you're in the market for a new pipette, consider purchasing a Sapphire tip.

Sapphire pipette tips are made of medical-grade polypropylene and are available in ten, twenty, and thirty-five ul volumes. Each tip features graduations and is available in standard and low-retention filter options. Because each tip is made from a pure virgin material, it ensures maximum recovery. They are packaged in sterile containers to maintain their sterility. They are compatible with the most popular brands of pipettors.

These universal tips are available in several sizes to accommodate various liquid handling applications. The low-retention and filter tips are ideal for samples that have low adhesion, while the standard tips reduce sample adhesion. The filtered tips prevent the transfer of aerosols and biological material. Additionally, they do not contain any additives, making them a safe and effective choice for daily liquid handling. You'll appreciate these benefits and start working in your laboratory today!

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